Reply to Rodgers: Does Myostatin Induce Insulin Resistance?

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Reply to Rodgers and Rowe ( 2002 )

That a theory fits data is meaningful only if it was plausible that the theory would not fit. S. Roberts and H. Pashler (2000) knew of no enduring theories initially supported by good fits alone (good fits, i.e., where it was not clear that the theory could have plausibly failed to fit). J. L. Rodgers and D. C. Rowe (2002) claimed to provide 6 examples. Their 3 nonpsychological examples (Kepler...

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acute and delayed response of myostatin and insulin resistance to circuit resistance exercise

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Endothelial Transcytosis of Insulin: Does It Contribute to Insulin Resistance?

Most research on insulin resistance has focused on impaired signaling at the level of target tissues like skeletal muscle. Insulin delivery is also important and includes recruitment and perfusion of capillaries bearing insulin, but also the transit of insulin across the capillary endothelium. The mechanisms of this second stage (insulin transcytosis) and whether it contributes to insulin resis...

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Where Does Insulin Resistance Start?

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 2014

ISSN: 0021-9258

DOI: 10.1074/jbc.o114.580621